AICAR
- 99%+ HPLC Purity — Independently verified by accredited US laboratory
- Endotoxin-Screened — LAL tested, LPS-free, endotoxin report available
- GMP-Certified Manufacturing — USA facility, ISO 9001:2015
- Lyophilized for Stability — Shipped cold-packed, intact for reconstitution
Add essential supplies:
For laboratory research use only. Not for human or veterinary use.
About AICAR
AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a high-purity research peptide widely used in metabolic and cellular research. It is a nucleotide analogue studied for its potential role in AMPK pathway activation. Supplied as a lyophilized powder, AICAR is intended only for laboratory and preclinical research purposes and not for human or animal consumption.
In controlled research environments, AICAR serves as a tool for investigating cellular energy regulation, mitochondrial responses, and metabolic signaling. Researchers value this compound for its reproducible purity and consistent performance in sensitive in-vitro assays.
AICAR At-a-Glance
Key specifications and quality details for AICAR research peptide:
Compound Name
AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide)
Compound Type
High-purity research peptide / nucleotide analogue
Mechanism
AMPK activator / cellular energy regulation tool
Purity
≥98–99% verified by HPLC
Form
Lyophilized powder
Intended Use
In-vitro and preclinical research only
Quality Verification
Certificate of Analysis (COA) and identity verification available
Not for Consumption
Strictly research use only
Storage
–20°C or below; protect from moisture and light
Solvent Recommendations
Reconstitute in sterile water, PBS, or DMSO per lab protocols
Potential Research Benefits
Research applications and laboratory investigations using AICAR. Note: All potential benefits are strictly for research applications. No human or clinical claims are made.
Metabolic Signalling Studies
AICAR is used to study AMPK pathway activation and cellular energy homeostasis.
Glucose and Fat Metabolism
Research suggests it may support laboratory investigations of metabolic pathways.
Mitochondrial Function
Used in cell studies examining mitochondrial responses under energy stress.
Preclinical Assays
Supports controlled experiments for exploring biochemical responses in vitro.
How AICAR Works in Research
Mechanism overview for laboratory research contexts:
Cellular Uptake
AICAR enters cells via nucleoside transporters.
Phosphorylation
Converted to ZMP, an AMP mimetic, within cells.
AMPK Activation
Engages the AMPK pathway, studied for energy regulation.
Lab Application
Helps researchers explore metabolic pathways, mitochondrial activity, and biochemical responses.
Suggested Research Use / Usage Notes
Guidelines for safe and effective use in laboratory settings:
- Do not use this compound outside approved laboratory settings.
- Ensure all research personnel are trained in chemical handling safety.
Applications
In-vitro cellular assays, preclinical metabolic studies
Handling
Use proper PPE: gloves, lab coat, and eye protection
Reconstitution
Sterile water, PBS, or DMSO; follow lab protocol
Dosing
Accurately weigh using calibrated lab balances
Safety
Do not ingest; for laboratory personnel only
Documentation
Maintain COA and batch records for reproducibility
Storage Instructions
Temperature
–20°C or below for long-term stability
Protection
Shield from moisture, light, and heat
Reconstituted Storage
2–8°C; minimize freeze-thaw cycles by aliquoting
Shelf Life
Stable under recommended conditions; follow lab storage protocols
Medical Disclaimer
AICAR is a research chemical intended for laboratory and educational use only. It is not approved for human or veterinary consumption and cannot diagnose, treat, cure, or prevent any disease. The information provided reflects research applications, not clinical advice.
