KPV
- 99%+ HPLC Purity — Independently verified by accredited US laboratory
- Endotoxin-Screened — LAL tested, LPS-free, endotoxin report available
- GMP-Certified Manufacturing — USA facility, ISO 9001:2015
- Lyophilized for Stability — Shipped cold-packed, intact for reconstitution
Add essential supplies:
For laboratory research use only. Not for human or veterinary use.
About KPV
KPV (Lysine-Proline-Valine) is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone (alpha-MSH). It is supplied here as a lyophilized powder at 99%+ HPLC purity for laboratory research use only.
This material is a research chemical. It is not a medicine, is not for human or veterinary use, and no administration, dosing or handling-in-humans guidance is provided.
What is KPV?
KPV is a short, highly stable tripeptide fragment of alpha-MSH. It is widely used as a reference compound in melanocortin signalling and inflammatory pathway research.
- Melanocortin research target: studied in vitro for interaction with melanocortin receptor pathways expressed on immune and intestinal cell lines.
- Origin: a naturally occurring fragment sequence of alpha-MSH, produced here by synthetic peptide synthesis.
- Distinct from Melanotan II: KPV lacks the sequence associated with MC1R-driven melanogenesis in published receptor studies.
Published research context
The following summarises third-party in-vitro and animal-model literature. These are laboratory observations only and are not human outcomes, efficacy claims or evidence of any therapeutic use.
Intestinal cell models
Preclinical studies have examined KPV in colonic epithelial cell cultures and rodent colitis models, reporting effects on NF-kappaB-associated inflammatory signalling in those models.
Dermatological cell models
In-vitro keratinocyte and skin-model studies have investigated KPV in relation to pro-inflammatory cytokine expression.
Antimicrobial assays
Laboratory assays have reported activity of KPV against cultured Staphylococcus aureus and Candida albicans isolates.
Wound-model research
Animal-model work has examined KPV in tissue repair assays measuring local cytokine activity.
Why researchers select this material
Laboratory handling characteristics reported for this compound:
- Short, chemically simple sequence that is straightforward to reconstitute and quantify.
- High stability of the lyophilized powder under recommended cold storage.
- Well-represented in published in-vitro and animal-model literature, supporting protocol comparison.
- Supplied at 99%+ HPLC purity with published batch documentation.
Frequently Asked Questions
KPV peptide: specification and research context
KPV is the C-terminal tripeptide (Lys-Pro-Val) of alpha-melanocyte-stimulating hormone, CAS 67727-97-3, molecular formula C₁₆H₃₀N₄O₄ at 342.43 g/mol. It is supplied as a lyophilized powder in a 5mg vial at 99%+ purity, with larger mg options selectable above; the displayed price updates with the selected strength and vial count.
Published in-vitro and preclinical literature examines KPV in models of melanocortin receptor signalling and inflammatory pathway modulation. Those are laboratory findings in cell and animal models only; they are not human outcomes and nothing on this page should be read as evidence of a benefit, effect or use in people.
This product is supplied for laboratory research use only. It is not a medicine, is not for human or veterinary use, and no administration, dosing or handling-in-humans guidance is provided.
- Strength: 5mg vial (additional mg options available)
- Purity: 99%+ HPLC · Reference LPKPV-01
- CAS 67727-97-3 · C₁₆H₃₀N₄O₄ · 342.43 g/mol
- Form: lyophilized powder — research use only
Review the matching batch documentation in our HPLC testing library, compare strengths across the independently tested research peptide catalog, or ask about volume pricing on the bulk offers page.
