SS-31 (Elamipretide)
- 99%+ HPLC Purity — Independently verified by accredited US laboratory
- Endotoxin-Screened — LAL tested, LPS-free, endotoxin report available
- GMP-Certified Manufacturing — USA facility, ISO 9001:2015
- Lyophilized for Stability — Shipped cold-packed, intact for reconstitution
Add essential supplies:
For laboratory research use only. Not for human or veterinary use.
About SS-31 (Elamipretide)
While most antioxidants try to clean up cellular waste after it has already caused damage, SS-31 (Elamipretide) works 'upstream' to fix the source of energy production itself. As a first-in-class mitochondria-targeted tetrapeptide, SS-31 is designed to penetrate the cellular membrane and stabilize the very structure of the mitochondria.
By targeting cardiolipin—a critical phospholipid found only in the inner mitochondrial membrane—SS-31 restores the 'biological engine' of the cell, making it a premier research tool for treating mitochondrial dysfunction, age-related decline, and chronic fatigue.
What is SS-31 (Elamipretide)?
SS-31 is a small, synthetic tetrapeptide (D-Arg-Dmt-Lys-Phe-NH2) that selectively accumulates in the inner mitochondrial membrane (IMM).
- Cardiolipin Stabilizer: SS-31 binds with high affinity to cardiolipin, preventing its oxidation and maintaining the structural integrity of mitochondrial cristae.
- ATP Optimization: By stabilizing the electron transport chain 'supercomplexes,' it allows for more efficient energy (ATP) production with fewer harmful byproducts.
- ROS Scavenging: It significantly reduces the production of Reactive Oxygen Species (ROS) at the source, preventing the oxidative stress that leads to cellular aging.
How Effective is SS-31?
Restores Exercise Capacity
Clinical research shows that SS-31 can reverse age-related declines in muscle performance, significantly improving endurance and fatigue resistance.
Cardiovascular Protection
It has been shown to improve left ventricular function and reduce cardiac fibrosis by restoring mitochondrial bioenergetics in the heart.
Neurovascular Coupling
In aged models, SS-31 rescues the communication between neurons and blood vessels, leading to measurable improvements in spatial memory and motor learning.
Renal Support
It accelerates the recovery of ATP in the kidneys following ischemic injury, protecting against tubular damage and chronic kidney decline.
Top Benefits of SS-31 Peptide
Why is SS-31 a centerpiece in advanced longevity and performance protocols?
- Direct Mitochondrial Repair: It doesn't just mask fatigue; it repairs the structural 'bottleneck' that limits cellular energy output.
- Improves Metabolic Flexibility: By optimizing the electron transport chain, it helps the body switch more efficiently between fuel sources.
- Combats 'Inflammaging': By lowering mitochondrial ROS, it prevents the activation of inflammatory pathways like the NLRP3 inflammasome.
- Synergistic Potential: It pairs exceptionally well with MOTS-c; while SS-31 repairs the structure of the mitochondria, MOTS-c increases the metabolic demand and capacity.
