MOTS-C 10mg (10 Vials)

Overview

MOTS-C is a mitochondrial-derived peptide studied in laboratory models for its role in cellular signaling, mitochondrial function, and metabolic pathway analysis. Research references describe its involvement in nuclear gene regulation, energy-related signaling, and cellular adaptation under experimental conditions. These references are included solely for scientific context and do not imply therapeutic or clinical use. This product is not offered for human or veterinary use.

MOTS-c: Structure

Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

Molecular Formula: C₁₀₆H₁₇₅N₃₁O₃₂S₂

Molecular Weight: 2174.64 g/mol

PubChem SID: 255386757

CAS Number: 1627580-64-6

Synonyms: Mitochondrial open reading frame of the 12S rRNA-c, MT-RNR1

Source: Wikipedia

MOTS-c: Research

MOTS-C is used in laboratory research to examine mitochondrial homeostasis, cellular stress responses, and metabolic signaling pathways in controlled experimental systems. Published studies may investigate AMPK-related signaling, mitochondrial adaptation, oxidative-stress responses, and bone-cell model behavior. Any references to aging, bone, or metabolic pathways are provided only for research context and do not imply therapeutic, diagnostic, or clinical use.

Referenced Citations

Yu WD, Kim YJ, Cho MJ, Seok J, Kim GJ, Lee CH, Ko JJ, Kim YS, Lee JH. The mitochondrial-derived peptide MOTS-c promotes homeostasis in aged human placenta-derived mesenchymal stem cells in vitro. Mitochondrion. 2021 May;58:135-146. doi: 10.1016/j.mito.2021.02.010. Epub 2021 Feb 24. PMID: 33639272.

Crescenzo R, Bianco F, Mazzoli A, Giacco A, Liverini G, Iossa S. A possible link between hepatic mitochondrial dysfunction and diet-induced insulin resistance. Eur J Nutr. 2016 Feb;55(1):1-6. doi: 10.1007/s00394-015-1073-0. PMID: 26476631.

Mohtashami Z, Singh MK, Salimiaghdam N, Ozgul M, Kenney MC. MOTS-c, the Most Recent Mitochondrial Derived Peptide in Human Aging and Age-Related Diseases. Int J Mol Sci. 2022 Oct 9;23(19):11991. doi: 10.3390/ijms231911991. PMID: 36233287; PMCID: PMC9570330.

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The products available on this website are intended solely for in-vitro research purposes (Latin: “in glass”), meaning they are used in experiments conducted outside a living organism. These products are not medicines or drugs, have not been evaluated or approved by the U.S. Food and Drug Administration (FDA), and are not intended to diagnose, treat, cure, or prevent any disease or medical condition. Any administration to humans or animals, whether by ingestion, injection, or other means, is strictly prohibited by law.